Enrique Lafuente Ferrari, 1898-1985

HIV / AIDS : Vertical Transmission Enrique

C1py00484k 1890..1898

End-functionalized polyethylene oxides containing cleavable acetal and clickable azide terminal groups (PEO-acetal-N3 and N3-acetal-PEO-acetal-N3) were obtained by the reaction between commercially available PEOs and 2-chloroethyl vinyl ether using pyridinium p-toluenesulfonate. This results in acetal-linkages which can be further functionalized by nucleophilic displacement with sodium azide. B...

Hilde Mangold-Pröscholdt (1898 – 1924)

In the history of medicine, few women were awarded an eponym. One can assume that this doesn’t have anything to do with their second X-chromosome or the weight of their brains. Most probably, it was the era that was not on their side. In the time period wherein most eponyms were given, women had almost no access to higher education. There are a few exceptions of course, such as Marie Curie or V...

Helen B. Taussig (1898-1986)

Together with Alfred Blalock, Helen Taussig rose to fame because of the Blalock-Taussig shunt. This is a surgical procedure in children who suffer from hypoxia because of a congenital cardiac malformation. Because of this affliction, they are blue. Less known is the fact that dr. Taussig also played a crucial role in the prohibition of thalidomide in the USA, the drug that had been responsible ...

Synaptic Vesicle Recycling: The Ferrari of endocytosis?

After neurotransmission, neurons internalize and recycle the membrane components of synaptic vesicles remarkably quickly; they may have a 'rebuilt, turbo-charged' endocytic engine to achieve these speeds.